Just outside the ancient medieval walls, is the Casa di Colombo, where the discoverer of the Americas lived in his youth. According to archival documents, Domenico Colombo, father of the great navigator, moved here in 1445, when Christopher Columbus was four years old. The ground floor of the house was used as a workshop, an attic with wooden beams divides it from the upper park, where the rooms for private use were located.

The guided tour will involve not only Columbus' House but also the Cloister of Sant'Andrea, rebuilt in the area behind the House and Porta Soprana to give the visitor a complete view of this area, still considered the medieval heart of Genoa.